Tobacco company 22nd Century Group reported net sales of $30.9 million in 2021, up 10.1% from 2020. The increase was due to higher contract manufacturing sales. Gross profit in 2021 was $2.1 million, compared to $1.4 million in the previous year. Gross margin in 2021 increased to 6.7% from 5.1% in the previous year.

Net sales for the fourth quarter of 2021 were $8 million, an increase of 8.9% over the same period last year. The increase was due to an increase in contract manufacturing sales. Gross profit for the fourth quarter of 2021 was $387,000, compared to $588,000 in the same period last year, as the favorable impact of large customer orders benefited the fourth quarter of last year.

"The past few months have been incredible as 22nd Century Group transitioned from a pure science and contract manufacturing company to one that sells branded VLN cigarettes, licenses valuable biotech IP and delivers highly advanced products in large and dynamic global end markets. A company that specializes in factory production lines," 22nd Century Group CEO Mish said in a statement.

“We received the much-anticipated FDA MRTP [Modified Risk Tobacco Product] designation on December 23 and immediately launched our VLN pilot program by the end of March. The first batch with FDA additional claims to help you reduce smoking VLN cigarettes rolled off our production line in late January.”

"Additionally, we have completed our point-of-sale materials to educate adult smokers on how to use VLN to change their relationship with highly addictive nicotine cigarettes, and we have partnered with Circle K for our first ever launch in over 150 subway stations. Preparing for the launch in Chicago stores ahead of the nationwide rollout of VLN. Our mission is to get this product into the hands of adult smokers as quickly as possible, 70% of whom want to quit and are looking for new and innovative products to help them reduce Smoking."

On February 28, 22nd Century Group announced that its VLN cigarettes would debut in South Korea.

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